Stopping Infections Without Causing Resistance - Antivirulence Drugs Could Be The Answer

Antivirulence drugs disarm pathogens rather than kill them, and although they could be effective in theory, antivirulence drugs have never been tested in humans. A new study to be published in the online journal mBio� on Tuesday, October 18 reveals these drugs have the potential to fight infection while avoiding the pitfalls of drug resistance. Traditional antibiotics aim to kill or stop the growth of pathogens, but antivirulence drugs prevent disease by neutralizing virulence factors, the specific proteins or toxins that a pathogen uses to establish an infection...

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