Researchers Link 'Epigenetic' Changes To Inflammation-Induced Colon Cancer

Johns Hopkins Kimmel Cancer Center scientists report that sharp rises in levels of reactive oxygen molecules, and the inflammation that results, trigger biochemical changes that silence genes in a pattern often seen in cancer cells. The researchers confirmed this gene-silencing effect in mice that develop inflammation-induced colon cancer. The study, reported Nov. 14 in Cancer Cell, is believed to be the first to identify a specific molecular mechanism linking inflammation to cancer epigenetics...

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